Drostanolone (Masteron)

🧪 What Is Drostanolone (Masteron)?

Drostanolone, commonly known by the brand name Masteron, is an anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It was originally developed for medical use, particularly in the treatment of breast cancer in women under the trade name Masteron Propionate (by Syntex) in the 1950s–60s.

Today, it’s primarily known in athletic and bodybuilding contexts for its muscle-hardening and physique-enhancing effects, though its non-medical use is illegal in many countries.

---

⚗️ Chemical Profile

• Chemical Name: Drostanolone Propionate / Drostanolone Enanthate

• Class: Anabolic-androgenic steroid (DHT derivative)

• Anabolic Rating: 62–130

• Androgenic Rating: 25–40

• Molecular Formula: C23H36O3

---

💪 Common Uses

In medical contexts:

• Previously prescribed as an anti-estrogenic agent in certain breast cancer treatments (due to its ability to inhibit estrogen-related effects).

In bodybuilding / athletic contexts (non-medical):

• Often used during cutting phases to help achieve a lean, defined, and “dry” look, as it reduces water retention.

• Known to enhance muscle hardness and vascularity, especially when body fat levels are already low.

• Sometimes used in combination with other compounds like Testosterone, Winstrol (Stanozolol), or Trenbolone for contest preparation.

---

⚖️ Legal Status

• Controlled Substance: Yes — in most countries (including the U.S., U.K., Canada, and Australia), Drostanolone is a Schedule III controlled substance, making possession or sale without a prescription illegal.

• Medical Availability: Very limited; it’s rarely prescribed in modern medicine.

---

⚠️ Potential Side Effects

Because it’s a synthetic steroid, Masteron carries health risks — even when used responsibly under medical supervision. Possible side effects include:

• Suppression of natural testosterone production

• Acne and oily skin

• Hair loss (especially in genetically prone individuals)

• Mood changes or aggression

• Cholesterol imbalance (lowered HDL, raised LDL)

• Virilization in women (deepened voice, hair growth, menstrual irregularities)

---

🧬 Half-Life and Detection

• Masteron Propionate: Half-life ~2–3 days

• Masteron Enanthate: Half-life ~7–10 days

• Detection Time: Can remain detectable in urine for several weeks, depending on the form used.

---

⚖️ Safer Legal Alternatives

For athletes who want similar physique-enhancing results without legal or health risks, several natural or legal “cutting” supplements are available. These alternatives often:

• Support fat metabolism

• Help retain lean muscle mass

• Improve energy and vascularity
  without using synthetic hormones.